Many peoples are exposed daily to cosmetics, pharmaceutical and packaged food products. These products contain para-hydroxybenzoic acid esters (Parabens). Parabens are synthetically produced preservatives used in personal care products, food and drink, medicines and pharmaceutical preparations. Parabens are readily absorbed through the skin and the gut and excreted in urine. However, some of these compounds may be retained in the body. Parabens have been measured in blood and urine including that of pregnant women, amniotic fluid, placental tissue, cord blood and breast tissue. Parabens are also widespread in our environment. There are many forthcoming researches evidenced that Parabens and Para-hydroxybenzoic acid may act as estrogenic endocrine disruptors. Parabens may increase breast cancer risk, particularly if exposure occurs during critical periods of development. Parabens have been implicated in the proliferation of breast cancer and marine toxicity. This review has been focused on the vital role and research findings of the published literature regarding the deleterious effects of the Parabens.
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